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KMID : 1039920150220030173
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Neonatal Medicine
2015 Volume.22 No. 3 p.173 ~ p.176
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A Case of Lactobacillus Bacteremia during Probiotic Supplementation in a Very Preterm Infant with Short Bowel Syndrome
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Kim Seon-Nyo
Lee Hae-Yun
Kim Sae-Yun
Lee Byung-Kook
Jung Young-Hwa
Huh Joo-sun
Seo Jae-Gu
Shin Seung-Han
Kim Ee-Kyung
Kim Han-Suk
Choi Jung-Hwan
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Abstract
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Probiotics are living micro-organisms that beneficially affect the composition of the host intestinal microflora. In very preterm infants, probiotics reportedly help reduce necrotizing enterocolitis (NEC), invasive fugal colonization and sepsis, and enable the establishment of complete enteral feeding at an earlier stage. However, emerging evidence has indicated the risk of potential side effects of probiotic use, such as gut organism translocation, including probiotic organisms, in infants that are more premature. In the present report, we describe a case of Lactobacillus bacteremia in a very preterm infant with short bowel syndrome. Lactobacillus sepsis developed during the therapeutic use of this organism for diarrhea and diarrhea-related malabsorption. The organism isolated from the blood sample was found to be of the same strain as that administered, by using molecular techniques. The findings of the present case suggest that probiotics should be carefully used, particularly in very preterm infants with altered intestinal permeability such as short bowel syndrome.
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KEYWORD
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Probiotics, Lactobacillus, Very preterm infant, Short bowel syndrome, Bacteremia
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